Animal Models of Inherited Metabolic Diseases

ond chapter is a clinical dissertation on Cushing's syndrome, combining basic and clinical science in a succinct and comprehensive marriage. Other outstanding articles within this book are the discussions of inhibin in Debeljuk and Rettori's chapter on gonadal hormones and gonadotropin secretion and the opioid regulation of pituitary secretion by Frantz et al., with a lucid explanation of the role and chemistry of enkephalins and endorphins. Well documented is the historical development of the association between brain opiates and pituitary control. The paper by Lipsett et al. on the catechol estrogens illustrates well the link between the endocrinologist and the neuroendocrinologist and, in doing so, philosophically pulls all the chapters together. While the chapter on fertilization seems a little out of place in this text, as does that portion devoted to immunology, this is overall an excellent text addressing a specific topic in a fine and well-executed fashion. It can successfully address both the novice and the expert.